Programming ligatures and `locl`

Recently many programming typefaces provides ligatures for operators, i.e., `!=` will be look like `≠`. However some operators may have different meaning in different languages, for example, `/=`, the meaning of this symbol in Haskell differs from that in JavaScript.

So consider a similar situation that the same letter has different shapein different langauges, is it possible to provide different ligarues for different programming languages using `locl` feature?